ACTA OPHTALMOLOGICA, 2016, Vol.42(2)
SYSTEMIC MANIFESTATIONS OF PSEUDOEXFOLIATION
Tatjana Šarenac Vulović1,2, Sunčica Srećković1,2, Nenad Petrović1,2, Dušan Todorović2
1Ophthalmology Clinic, Clinical Center Kragujevac,
2Faculty of Medicine, Kragujevac
Pseudoexfoliative syndrome is characterized by abnormal production and accumulation of pseudoexfoliative material in different tissues in the body (lung, liver, heart, kidney, gall bladder, blood vessels, meninges, eye, extraocualr muscles). It is supposed that about 70 million people in the world have PEX. High intraocular pressure is detected in 0.25% of them, and one third have developed pseudoexfoliative glaucoma. Some studies indicated that there is tight connection between pseudoexfoliation and systemic diseases. Cardiovascular and cerebrovascular diseases are most common. Examination of the patients with PEX is a huge challenge for the ophthalmologist, and includes team approach for early detection and treatment of its systemic manifestation (internist, vascular surgeon, otolaryngologist, and neurologist). Acta Ophthalmologica 2016;42(2):5-9.
Key words: pseudoexfoliation, cardiovascular, cerebrovascular, sensoneural hearing loss, Alzheimer
2016, Vol. 42(2)